| Defiance Games/Schedule (2025-2026) | |||||
| DATE | LEAGUE | ROUND | H/A | OPPONENT | RESULT |
| Nov.1,2025Nov.1,25 |  NAIA | Regular Season - Round 18 RS Rd 18 | - | Defiance KSU-Tuscarawas | 67-56  |
| Nov.5,2025Nov.5,25 | NAIA | Regular Season - Round 22 RS Rd 22 | - | Defiance Goshen | 75-57 |
| Nov.11,2025Nov.11,25 | NAIA | Regular Season - Round 28 RS Rd 28 | - | Defiance Miami Middletown | 83-73 |
| Nov.15,2025Nov.15,25 |  NCAA1 | Regular Season - Round 13 RS Rd 13 | - | Defiance Oakland | 47-113  |
| Nov.15,2025Nov.15,25 | NAIA | Regular Season - Round 32 RS Rd 32 | - | OaklandDefiance | History  |
| Nov.17,2025Nov.17,25 | NAIA | Regular Season - Round 34 RS Rd 34 | - |  Lawrence TechDefiance | 70-59 |
| Nov.21,2025Nov.21,25 | NAIA | Regular Season - Round 38 RS Rd 38 | - | Defiance Wright St. LC | 81-61 |
| Nov.22,2025Nov.22,25 | NAIA | Regular Season - Round 39 RS Rd 39 | - | Defiance WAU | 94-91 |
| Nov.25,2025Nov.25,25 | NAIA | Regular Season - Round 42 RS Rd 42 | - |  CornerstoneDefiance | 89-68 |
| Nov.29,2025Nov.29,25 | NAIA | Regular Season - Round 45 RS Rd 45 | - | Miami Middletown - Defiance | History |
| Dec.3,2025Dec.3,25 | NAIA | Regular Season - Round 49 RS Rd 49 | - | Defiance Lourdes | 64-81 |
| Dec.6,2025Dec.6,25 | NAIA | Regular Season - Round 52 RS Rd 52 | - |  SHUDefiance | 55-61 |
| Dec.13,2025Dec.13,25 | NAIA | Regular Season - Round 59 RS Rd 59 | - |  UNOHDefiance | 78-71 |
| Dec.17,2025Dec.17,25 | NAIA | Regular Season - Round 63 RS Rd 63 | - | Defiance Indiana Tech | 53-64 |
| Dec.22,2025Dec.22,25 | NCAA1 | Regular Season - Round 50 RS Rd 50 | - | Defiance W.Michigan | 57-94 |
| Dec.22,2025Dec.22,25 | NAIA | Regular Season - Round 68 RS Rd 68 | - | W.MichiganDefiance | 94-57 |
| Dec.30,2025Dec.30,25 | NAIA | Regular Season - Round 72 RS Rd 72 | - | Defiance Rochester, MI | 87-85 |
| Jan.3,2026Jan.3,26 | NAIA | Regular Season - Round 76 RS Rd 76 | - |  UM-DearbornDefiance | 71-94 |
| Jan.7,2026Jan.7,26 | NAIA | Regular Season - Round 80 RS Rd 80 | - | Defiance Madonna | 69-101 |
| Jan.11,2026Jan.11,26 | NAIA | Regular Season - Round 83 RS Rd 83 | - |  Aquinas Coll.Defiance | 71-75 |
| Jan.14,2026Jan.14,26 | NAIA | Regular Season - Round 86 RS Rd 86 | - |  ClearyDefiance | 69-75 |
| Jan.17,2026Jan.17,26 | NAIA | Regular Season - Round 89 RS Rd 89 | - | DefianceLawrence Tech | 64-67 |
| Jan.21,2026Jan.21,26 | NAIA | Regular Season - Round 93 RS Rd 93 | - | Rochester, MIDefiance | 79-75 |
| Jan.24,2026Jan.24,26 | NAIA | Regular Season - Round 96 RS Rd 96 | - | DefianceSHU | 78-86 |
| Jan.28,2026Jan.28,26 | NAIA | Regular Season - Round 99 RS Rd 99 | - | LourdesDefiance | 75-74 |
| Jan.31,2026Jan.31,26 | NAIA | Regular Season - Round 102 RS Rd 102 | - | Indiana TechDefiance | 75-78 |
| Feb.4,2026Feb.4,26 | NAIA | Regular Season - Round 105 RS Rd 105 | - | DefianceCornerstone | 60-71 |
| Feb.7,2026Feb.7,26 | NAIA | Regular Season - Round 108 RS Rd 108 | - | DefianceUNOH | 64-66 |
| Feb.11,2026Feb.11,26 | NAIA | Regular Season - Round 112 RS Rd 112 | - | MadonnaDefiance | 93-73 |
| Feb.14,2026Feb.14,26 | NAIA | Regular Season - Round 115 RS Rd 115 | - | DefianceUM-Dearborn | 93-80 |
| Feb.18,2026Feb.18,26 | NAIA | Regular Season - Round 119 RS Rd 119 | - | DefianceCleary | 66-70 |
| Feb.21,2026Feb.21,26 | NAIA | Regular Season - Round 122 RS Rd 122 | - | DefianceAquinas Coll. | 84-75 |
